From New York and North Jersey:

Follow the Garden State Pwky to mile Zero. At the end bear left on Route 109 over the bridge and into Cape May City. As you cross the small bridge with boats on either side, stay to the right on Lafayette Street. At the first light in town, turn left onto Madison. Go 3 blocks to the water tower and turn right on Columbia. Proceed 3 blocks to the Mainstay Inn on the right corner. Park in the fifteen-minute loading zone while checking in.

From Philadelphia and West:

Follow Interstate 76 East and cross the Walt Whitman Bridge. Stay on Route 42 towards Atlantic City. Bear right on Route 55 South. After 40 minutes this will put you on Route 47 south, then 347 south and back to 47 south. Follow 47 south to the Garden State Parkway south. (see directions above). From Lancaster area, you may want to use the Commodore Barry Bridge and follow Route 322 east to Route 55 south.

From Baltimore and Washington:

Follow Interstate 95 North towards Wilmington. Below Wilmington follow signs to the Delaware Memorial Bridge and the New Jersey Turnpike. Just after crossing the bridge, follow Route 40 east towards Atlantic City. After the town of Elmer, watch for Route 55 south. (see directions above).

From Washington and points south

You may want to consider the Cape May Lewes Ferry. From the Washington beltway (495), take Route 50 east across the Chesapeake Bay Bridge. In the Wye Mills area, take Route 404 east, Route 16 east, Route 1 south and follow signs to the Ferry Terminal in Lewes, Delaware. If you are early, the historic district of Lewes is great! Good shops, museums and places for lunch. You can make reservations on the ferry ($5 extra) by calling 1-800-643-3779 or visit their web site. It is a nice 70-minute cruise across the bay.